![Frontiers | Advances in the research of the mechanism of secondary resistance to imatinib in gastrointestinal stromal tumors Frontiers | Advances in the research of the mechanism of secondary resistance to imatinib in gastrointestinal stromal tumors](https://www.frontiersin.org/files/Articles/933248/fonc-12-933248-HTML/image_m/fonc-12-933248-g001.jpg)
Frontiers | Advances in the research of the mechanism of secondary resistance to imatinib in gastrointestinal stromal tumors
![Cancers | Free Full-Text | Tyrosine Kinase Inhibitors in Cancer: Breakthrough and Challenges of Targeted Therapy Cancers | Free Full-Text | Tyrosine Kinase Inhibitors in Cancer: Breakthrough and Challenges of Targeted Therapy](https://www.mdpi.com/cancers/cancers-12-00731/article_deploy/html/images/cancers-12-00731-g001.png)
Cancers | Free Full-Text | Tyrosine Kinase Inhibitors in Cancer: Breakthrough and Challenges of Targeted Therapy
![Mechanism of action of imatinib. A) Under physiological conditions, ATP... | Download Scientific Diagram Mechanism of action of imatinib. A) Under physiological conditions, ATP... | Download Scientific Diagram](https://www.researchgate.net/profile/Suzanne-George-2/publication/41453779/figure/fig1/AS:202620166774788@1425319820981/Mechanism-of-action-of-imatinib-A-Under-physiological-conditions-ATP-binds-to-KIT-or_Q320.jpg)
Mechanism of action of imatinib. A) Under physiological conditions, ATP... | Download Scientific Diagram
![New treatment strategies for advanced-stage gastrointestinal stromal tumours | Nature Reviews Clinical Oncology New treatment strategies for advanced-stage gastrointestinal stromal tumours | Nature Reviews Clinical Oncology](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41571-022-00606-4/MediaObjects/41571_2022_606_Fig2_HTML.png)
New treatment strategies for advanced-stage gastrointestinal stromal tumours | Nature Reviews Clinical Oncology
![Mechanism of action of imatinib. A) Under physiological conditions, ATP... | Download Scientific Diagram Mechanism of action of imatinib. A) Under physiological conditions, ATP... | Download Scientific Diagram](https://www.researchgate.net/publication/303477988/figure/fig1/AS:365308083752963@1464107642410/n-the-gastro-intestinal-stromal-tumor-cell-A-regorafenib-inhibits-phosphorylation-of_Q320.jpg)
Mechanism of action of imatinib. A) Under physiological conditions, ATP... | Download Scientific Diagram
![Effects of Imatinib on Normal Hematopoiesis and Immune Activation - Appel - 2005 - STEM CELLS - Wiley Online Library Effects of Imatinib on Normal Hematopoiesis and Immune Activation - Appel - 2005 - STEM CELLS - Wiley Online Library](https://stemcellsjournals.onlinelibrary.wiley.com/cms/asset/2025e06c-911d-4803-8057-a5a54daba7ef/mfig001.jpg)
Effects of Imatinib on Normal Hematopoiesis and Immune Activation - Appel - 2005 - STEM CELLS - Wiley Online Library
![Intrigue: Phase III study of ripretinib versus sunitinib in advanced gastrointestinal stromal tumor after imatinib | Future Oncology Intrigue: Phase III study of ripretinib versus sunitinib in advanced gastrointestinal stromal tumor after imatinib | Future Oncology](https://www.futuremedicine.com/cms/10.2217/fon-2019-0633/asset/images/medium/figure1.gif)
Intrigue: Phase III study of ripretinib versus sunitinib in advanced gastrointestinal stromal tumor after imatinib | Future Oncology
Glucose transporter‑1 inhibition overcomes imatinib resistance in gastrointestinal stromal tumor cells
![A decade of tyrosine kinase inhibitor therapy: Historical and current perspectives on targeted therapy for GIST - ScienceDirect A decade of tyrosine kinase inhibitor therapy: Historical and current perspectives on targeted therapy for GIST - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0305737210001933-gr2.jpg)