![A Narrative Pharmacological Review of Buprenorphine: A Unique Opioid for the Treatment of Chronic Pain | SpringerLink A Narrative Pharmacological Review of Buprenorphine: A Unique Opioid for the Treatment of Chronic Pain | SpringerLink](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs40122-019-00143-6/MediaObjects/40122_2019_143_Fig4_HTML.png)
A Narrative Pharmacological Review of Buprenorphine: A Unique Opioid for the Treatment of Chronic Pain | SpringerLink
![IJMS | Free Full-Text | Distinct Effects of Nalmefene on Dopamine Uptake Rates and Kappa Opioid Receptor Activity in the Nucleus Accumbens Following Chronic Intermittent Ethanol Exposure IJMS | Free Full-Text | Distinct Effects of Nalmefene on Dopamine Uptake Rates and Kappa Opioid Receptor Activity in the Nucleus Accumbens Following Chronic Intermittent Ethanol Exposure](https://pub.mdpi-res.com/ijms/ijms-17-01216/article_deploy/html/images/ijms-17-01216-ag.png?1581074634)
IJMS | Free Full-Text | Distinct Effects of Nalmefene on Dopamine Uptake Rates and Kappa Opioid Receptor Activity in the Nucleus Accumbens Following Chronic Intermittent Ethanol Exposure
![Activation of opioid receptors in the enteric nervous system. MOR mu... | Download Scientific Diagram Activation of opioid receptors in the enteric nervous system. MOR mu... | Download Scientific Diagram](https://www.researchgate.net/publication/355537946/figure/fig1/AS:1082947297902592@1635206164135/Activation-of-opioid-receptors-in-the-enteric-nervous-system-MOR-mu-opioid-receptor-DOR.png)
Activation of opioid receptors in the enteric nervous system. MOR mu... | Download Scientific Diagram
![Src‐dependent phosphorylation of μ‐opioid receptor at Tyr336 modulates opiate withdrawal | EMBO Molecular Medicine Src‐dependent phosphorylation of μ‐opioid receptor at Tyr336 modulates opiate withdrawal | EMBO Molecular Medicine](https://www.embopress.org/cms/asset/886cb2b5-939d-4499-b439-38fc60ffd0bd/emmm201607324-abs-0001-m.jpg)
Src‐dependent phosphorylation of μ‐opioid receptor at Tyr336 modulates opiate withdrawal | EMBO Molecular Medicine
![Frontiers | Traumatic Stress-Induced Vulnerability to Addiction: Critical Role of the Dynorphin/Kappa Opioid Receptor System Frontiers | Traumatic Stress-Induced Vulnerability to Addiction: Critical Role of the Dynorphin/Kappa Opioid Receptor System](https://www.frontiersin.org/files/Articles/856672/fphar-13-856672-HTML/image_m/fphar-13-856672-g001.jpg)
Frontiers | Traumatic Stress-Induced Vulnerability to Addiction: Critical Role of the Dynorphin/Kappa Opioid Receptor System
![The Role of Dynorphin and the Kappa Opioid Receptor in the Symptomatology of Schizophrenia: A Review of the Evidence - ScienceDirect The Role of Dynorphin and the Kappa Opioid Receptor in the Symptomatology of Schizophrenia: A Review of the Evidence - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0006322319313794-gr1.jpg)
The Role of Dynorphin and the Kappa Opioid Receptor in the Symptomatology of Schizophrenia: A Review of the Evidence - ScienceDirect
![Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands: Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands: Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience](https://pubs.acs.org/cms/10.1021/acschemneuro.9b00195/asset/images/large/cn-2019-00195v_0008.jpeg)
Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands: Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience
![Kappa-opioid receptor-dependent changes in dopamine and anxiety-like or approach-avoidance behavior occur differentially across the nucleus accumbens shell rostro-caudal axis - ScienceDirect Kappa-opioid receptor-dependent changes in dopamine and anxiety-like or approach-avoidance behavior occur differentially across the nucleus accumbens shell rostro-caudal axis - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0028390820304093-fx1.jpg)
Kappa-opioid receptor-dependent changes in dopamine and anxiety-like or approach-avoidance behavior occur differentially across the nucleus accumbens shell rostro-caudal axis - ScienceDirect
![Opioid withdrawal symptoms, a consequence of chronic opioid use and opioid use disorder: Current understanding and approaches to management - Pergolizzi - 2020 - Journal of Clinical Pharmacy and Therapeutics - Wiley Online Library Opioid withdrawal symptoms, a consequence of chronic opioid use and opioid use disorder: Current understanding and approaches to management - Pergolizzi - 2020 - Journal of Clinical Pharmacy and Therapeutics - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/0ebcd542-a70c-444c-95a4-ba4e2401a86e/jcpt13114-fig-0003-m.jpg)
Opioid withdrawal symptoms, a consequence of chronic opioid use and opioid use disorder: Current understanding and approaches to management - Pergolizzi - 2020 - Journal of Clinical Pharmacy and Therapeutics - Wiley Online Library
![Pharmaceuticals | Free Full-Text | Biased, Bitopic, Opioid–Adrenergic Tethered Compounds May Improve Specificity, Lower Dosage and Enhance Agonist or Antagonist Function with Reduced Risk of Tolerance and Addiction Pharmaceuticals | Free Full-Text | Biased, Bitopic, Opioid–Adrenergic Tethered Compounds May Improve Specificity, Lower Dosage and Enhance Agonist or Antagonist Function with Reduced Risk of Tolerance and Addiction](https://pub.mdpi-res.com/pharmaceuticals/pharmaceuticals-15-00214/article_deploy/html/images/pharmaceuticals-15-00214-g001.png?1644559817)
Pharmaceuticals | Free Full-Text | Biased, Bitopic, Opioid–Adrenergic Tethered Compounds May Improve Specificity, Lower Dosage and Enhance Agonist or Antagonist Function with Reduced Risk of Tolerance and Addiction
![Distinct Mu, Delta, and Kappa Opioid Receptor Mechanisms Underlie Low Sociability and Depressive-Like Behaviors During Heroin Abstinence | Neuropsychopharmacology Distinct Mu, Delta, and Kappa Opioid Receptor Mechanisms Underlie Low Sociability and Depressive-Like Behaviors During Heroin Abstinence | Neuropsychopharmacology](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fnpp.2014.126/MediaObjects/41386_2014_Article_BFnpp2014126_Fig1_HTML.jpg)